研究業績

2015年

原著論文

• "FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice"
  Yoshihiro Kino,Chika Washizu,Masaru Kurosawa,Mizuki Yamada,Hiroshi Doi,Toru Takumi,Hiroaki Adachi,Masahisa Katsuno,Gen Sobue,Geoffrey G. Hicks,Nobutaka Hattori,Tomomi Shimogori,Nobuyuki Nukina
  SCIENTIFIC REPORTS 6, 35236 (2015).

  • DOI: 10.1038/srep35236
• "RNA-Seq data mining approach identifies opalin as a reliable marker for myelinating oligodendrocytes"
  Jun-Ichi Satoh,Mika Takitani,Junko Miyoshi,Yoshihiro Kino
  Clinical and Experimental Neuroimmunology 7, 1, 66 (2015).

  • DOI: 10.1111/cen3.12240
• "RNA-Seq data analysis identifies the comprehensive profile of in vivo interferon-β-stimulated genes in multiple sclerosis"
  Jun-Ichi Satoh,Mika Takitani,Junko Miyoshi,Yoshihiro Kino
  Clinical and Experimental Neuroimmunology 7, 1, 39 (2015).

  • DOI: 10.1111/cen3.12268
• "Immunohistochemical characterization of CD33 expression on microglia in Nasu-Hakola disease brains"
  Jun-ichi Satoh,Yoshihiro Kino,Nobutaka Motohashi,Tsuyoshi Ishida,Saburo Yagishita,Kenji Jinnai,Nobutaka Arai,Kiyotaka Nakamagoe,Akira Tamaoka,Yuko Saito,Kunimasa Arima
  NEUROPATHOLOGY 35, 6, 529 (2015).

  • DOI: 10.1111/neup.12222
• "Legumain is expressed on macrophages in active demyelinating lesions of multiple sclerosis"
  Jun-Ichi Satoh,Naohiro Asahina,Shouta Kitano,Yoshihiro Kino
  Clinical and Experimental Neuroimmunology 6, 3, 304 (2015).

  • DOI: 10.1111/cen3.12208
• "Expression profiles of RNA-Seq-based grey matter-specific genes versus white matter-specific genes in grey matter lesions of multiple sclerosis"
  Jun-Ichi Satoh,Yoshihiro Kino
  Clinical and Experimental Neuroimmunology 6, 3, 289 (2015).

  • DOI: 10.1111/cen3.12218
• "Bioinformatics data mining approach indicates the expression of chromatin immunoprecipitation followed by deep sequencing (ChIP-Seq)-based hypoxia-inducible factor-1α target genes in periplaque lesions of multiple sclerosis"
  Jun-Ichi Satoh,Naohiro Asahina,Shouta Kitano,Yoshihiro Kino
  Clinical and Experimental Neuroimmunology 6, 2, 159 (2015).

  • DOI: 10.1111/cen3.12195
• "MicroRNA-seq data analysis pipeline to identify blood biomarkers for Alzheimer’s disease from public data"
  Jun-Ichi Satoh,Yoshihiro Kino,Shumpei Niida
  Biomarker Insights 10, 21 (2015).

  • DOI: 10.4137/BMIMI.S25132
• "FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis"
  Yoshihiro Kino,Chika Washizu,Masaru Kurosawa,Mizuki Yamada,Haruko Miyazaki,Takumi Akagi,Tsutomu Hashikawa,Hiroshi Doi,Toru Takumi,Geoffrey G. Hicks,Nobutaka Hattori,Tomomi Shimogori,Nobuyuki Nukina
  ACTA NEUROPATHOLOGICA COMMUNICATIONS 3, 24 (2015).

  • DOI: 10.1186/s40478-015-0202-6
• "Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice"
  Masaru Kurosawa,Gen Matsumoto,Yoshihiro Kino,Misako Okuno,Mizuki Kurosawa-Yamada,Chika Washizu,Harumi Taniguchi,Kazuhiro Nakaso,Toru Yanagawa,Eiji Warabi,Tomomi Shimogori,Takashi Sakurai,Nobutaka Hattori,Nobuyuki Nukina
  HUMAN MOLECULAR GENETICS 24, 4, 1092 (2015).

  • DOI: 10.1093/hmg/ddu522
• "Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins"
  Yoshihiro Kino,Chika Washizu,Masaru Kurosawa,Yoko Oma,Nobutaka Hattori,Shoichi Ishiura,Nobuyuki Nukina
  HUMAN MOLECULAR GENETICS 24, 3, 740 (2015).

  • DOI: 10.1093/hmg/ddu492
• "Bioinformatics Data Mining Approach Suggests Coexpression of AGTPBP1 with an ALS-linked Gene C9orf72."
  Kitano S,Kino Y,Yamamoto Y,Takitani M,Miyoshi J,Ishida T,Saito Y,Arima K,Satoh J
  Journal of Central Nervous System Disease 7, 15 (2015).
• "A Comprehensive Profile of ChIP-Seq-Based Olig2 Target Genes in Motor Neuron Progenitor Cells Suggests the Possible Involvement of Olig2 in the Pathogenesis of Amyotrophic Lateral Sclerosis."
  Satoh J,Asahina N,Kitano S,Kino Y
  Journal of central nervous system disease 7, 1 (2015).

  • DOI: 10.4137/JCNSD.S23210